Does the body produce butyrate naturally?

The body does produce butyrate, as it comes from the fermentation of certain fibres; but it may not always be enough, so some people then opt for a butyrate supplement.

Where does SAMe originate from?

SAMe, or S-adenosylmethionine, is a compound that occurs naturally in the body and is derived from the amino acid methionine. In supplemental form, SAMe is chemically created to be structurally the same as naturally occurring SAMe.

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